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Our research centres on the chemical synthesis, radiochemistry, preclinical development and clinical translation of metal-based radiopharmaceuticals for diagnostic PET imaging in cancer and other human diseases

synthesis
Radiochemistry
Preclinical
imaging
clinical
translation
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News

8th May 25

  • Patrick and co-workers publish in JACS Au with the article featuring on the cover. Photoradiosynthesis of 161Tb-labelled onartuzumab for radioimmunotherapy of gastric adenocarcinoma; JACS Au, 2025, in press

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15th April 25

  • Cesare publishes in Chem Commun with the article featuring on the cover. Light-induced chemistry for protein functionalisation; Chem. Commun., 2025, 61, 5234–5252. Highlighted as the ‘Cover feature’. DOI: 10.1039/D4CC06529H. Part of the themed collection: 2025 Pioneering Investigators

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15th April 25

  • Jonas and co-workers publish in Chem Sci  with the article featuring on the cover. Photoradiolabeling of onartuzumab with 99mTc and 188Re-tricarbonyl for radiotheranostics of gastric cancer; Chem. Sci., 2025, 6, 6219–6230. Highlighted as the ‘Cover feature’. DOI: 10.1039/D4SC08089K.

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8th April 25

  • Congratulations to Simon - who has completed the final stage of his PhD, presenting his thesis on 'Robots, Rings, and Radiopharmaceuticals'. We wish you all the best for the future!

 

31st Mar 25

  • We say goodbye to Volkan - thanks for all the hard work!

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3rd Mar 25

  • We welcome masters student Volkan Songur, who will also work on light-activated small molecules for the conjugation of radionuclides to proteins for potential applications in radio-imaging and therapy. Glad to have you with us, even if its only for a month!​
     

24th Feb 25

  • We welcome masters student Zuzana Simackova, who will work on new photo-activatable handles for the conjugation of radionuclides to targeting proteins. Good luck! 

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Funding

The Holland Lab thanks the following agencies for generous support of our research:

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  •   European Research Council (ERC) -  (Jason Holland, Starting Grant ERC-StG-2015, 'NanoSCAN' #676904)

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  •   Swiss National Science Foundation (SNSF)  -  (Jason Holland, SNSF Professorship PP00P2_163683)

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  •   Swiss Government Excellence Scholarship  -  (Faustine d'Orchymont, PhD Student Scholarship, 2017)

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  •   Department of Chemistry, University of Zurich

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  •   Chemical and Molecular Life Sciences Graduate School (CMSZH), University of Zurich

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  •   Krebsliga and the Krebsforschung Schweiz -  (Jason Holland, Research Grant KFS-4257-08-2017)

Contact

Prof. Dr Jason P. Holland

University of Zurich

Department of Chemistry

Winterthurerstrasse 190

Zurich, CH-8057

Switzerland

www.hollandlab.org​​

Tel: +41.44.63.53.990

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jason.holland[at]chem.uzh.ch

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