Our research centres on the chemical synthesis, radiochemistry, preclinical development and clinical translation of metal-based radiopharmaceuticals for diagnostic PET imaging in cancer and other human diseases
21st Feb 20
Jason publishes a collaborative article with the group of Prof. Neil Vasdev (Toronto) in Molecules
'Revisiting the Radiosynthesis of [18F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease'
10th Feb 20
Linus and Mirsche join the group as Bachelor's students. Welcome and good luck with your experiments!
3rd Jan 20
Jason publishes an article in Inorganic Chemistry
'Predicting the thermodynamic stability of zirconium radiotracers'
21st Nov 19
Simon and Rachael publish an article in the Journal of Nuclear Medicine
'Light-induced radiosynthesis of 89ZrDFO-azepin-onartuzumab for imaging the hepatocyte growth factor receptor'
7th Oct 19
Jason, Melanie, Simon, Rachael and Amaury publish a Concept article in Chemistry - A European Journal
'Photochemical reactions in the synthesis of protein-drug conjugates'
28th Aug 19
Angelo Frei and Eliane publish an article in Dalton Transactions
'Two is better than one: difunctional high-affinity PSMA probes based on a [CpM(CO)3] (M = Re/99mTc) scaffold'
24th Aug 19
Melanie publishes an article in Inorganic Chemistry
'Synthesis and photochemical studies on gallium and indium complexes of DTPA-PEG3-ArN3 for radiolabelling antibodies'
19th Aug 19
Patricia joins the group as a Master's student with expertise in analytical chemistry. Welcome!
16th Aug 19
Rachael, Jennifer, Faustine and Melanie present posters at ICBIC, Interlaken
Rachael wins the poster prize for her excellent work on 'Photoradiolabelled 68GaHBED-CC-azepin-MetMAb'. Congratulations!
13th Aug 19
Jason presents an invited lecture at the 19th International Conference on Biological Inorganic Chemistry (ICBIC), Interlaken.
1st Aug 19
Jennifer publishes an article in Chemical Science
'Multi-functionalised graphene nanoflakes as tumour-targeting theranostic drug-delivery vehicles'
15th July 19
Daniel joins the group as a post-doctoral scientist with expertise in sugar synthesis. Welcome!
12th June 19
Jason publishes perspective in Drug Target Review
'Radiochemistry and drug synthesis 'in a flash'
12th June 19
Amaury joins the group as a post-doctoral scientist with expertise in synthesis. Welcome!
23rd May 19
Jason publishes a collaborative study with Prof. Rachel Codd from the University of Sydney in Inorganic Chemistry
'Endo-Hydroxamic acid monomers for the assembly of a suite of non-native dimeric macrocyclic siderophores using metal-templated synthesis'
18th May 19
Rachael and Melanie publish an article in Bioconjugate Chemistry
'Photoradiosynthesis of 68Ga-labelled HBED-CC-azepin-MetMAb for immuno-PET of c-MET receptors'
23rd Apr 19
Our photoradiochemical technology is featured in a Press Release from the University of Zurich.
17th Apr 19
Jennifer receives the Alavi-Mandell Award from the Society of Nuclear Medicine and Molecular Imaging (SNMMI) for her paper in the Journal of Nuclear Medicine
'Advanced methods for radiolabeling multimodality nanomedicines for SPECT/MRI and PET/MRI'. Congratulations!
4th Apr 19
Faustine receives an extension for her Swiss Government Excellence Scholarship. Congratulations and keep up the great work!
22nd Mar 19
Rachael publishes an article in the Journal of Nuclear Medicine
'The impact of emerging bioconjugation chemistries on radiopharmaceuticals'.
7th Mar 19
Simon receives the Mathematics and Natural Science Semester Prize (Autumn 2018) for his Bachelor's thesis. Congratulations!
2nd Mar 19
Malay, Simon and Larissa publish an article in iScience
'Simultaneous photoradiochemical labelling of antibodies for immuno-PET '.
4th Feb 19
Larissa publishes an article in Chemical Communications
'Photoactive chelates for radiolabelling proteins'. Highlighted as the Cover Article
4th Feb 19
Rita Sala Faig joins the group as a visiting PhD student from the University of Barcelona. Welcome!
1st Feb 19
Jennifer, Faustine, Rachael, Florian and Melanie receive travel bursary awards to attend the International Society of Radiopharmaceutical Sciences (ISRS) conference in Beijing (May 2019). Congratulations!
18th Jan 19
Faustine wins the the award for 'Best Poster' at the Chemical and Molecular Sciences Zurich (CMSZH) retreat. Congratulations!
4th Dec 18
Malay and Larissa publish an article in Angewandte Chemie Int. Ed.
Highlighted as the Featured Article and Frontispiece
24th Sept 18
Jason is interviewed for an article feature in Chemistry World - 'The nuclear option' by James Mitchell Crow
The Holland Lab thanks the following agencies for generous support of our research:
European Research Council (ERC) - (Jason Holland, Starting Grant ERC-StG-2015, 'NanoSCAN' #676904)
Swiss National Science Foundation (SNSF) - (Jason Holland, SNSF Professorship PP00P2_163683)
Swiss Government Excellence Scholarship - (Faustine d'Orchymont, PhD Student Scholarship, 2017)
Department of Chemistry, University of Zurich
Chemical and Molecular Life Sciences Graduate School (CMSZH), University of Zurich
Krebsliga and the Krebsforschung Schweiz - (Jason Holland, Research Grant KFS-4257-08-2017)